Publications

Siletti C, Freeman M, Tu Z, Stevenson DM, Amador-Noguez D, Sauer JD, Huynh TN. C-di-AMP accumulation disrupts glutathione metabolism and virulence program expression in Listeria monocytogenes. bioRxiv

Tu Z, Stevenson DM, McCaslin D, Amador-Noguez D, Huynh TN (2024). The role of Listeria monocytogenes PstA in β-lactam resistance requires the cytochrome bd oxidase activity. Journal of Bacteriology

Huynh TN and Stewart V (2023). Purine catabolism by enterobacteria. Advances in Microbial Physiology.

Gall AG, Hsueh BY, Siletta C, Waters CM, Huynh TN (2021). NrnA is a linear dinucleotide phosphodiesterase with limited function in cyclic dinucleotide metabolism in Listeria monocytogenes. Journal of Bacteriology.

Jackson-Litteken CD, Ratliff CT, Kneubehl AR, Siletti C, Pack L, Lan R, Huynh TN, Lopez JE, Blevins JS. (2021). The diadenylate cyclase, CdaA, is critical for Borrelia turicatae virulence and physiology. Infection and Immunity.

Chow JTH, Gall AR, Johnson AK, Huynh TN (2021). Characterization of Listeria monocytogenes isolates from lactating dairy cows in a Wisconsin farm: antibiotic resistance, mammalian cell infection, and effects on the fecal microbiota. Journal of Dairy Science.

Massa SM, Sharma AD, Siletti C, Tu Z, Godfrey JJ, Gutheil WG, Huynh TN (2020).  C-di-AMP accumulation impairs muropeptide synthesis in Listeria monocytogenes. Journal of Bacteriology.

Pham HT, Nguyen THN, Vu NTM, Huynh TN, Zhu Y, Huynh A, Chakrabortti A, Marcellin E, Lo R, Howard C, Bansal N, Woodward J, Liang ZX, Turner MS (2018). Enhanced potassium or glycine betaine uptake or export of cyclic-di-AMP restores osmoresistance in a high cyclic-di-AMP Lactococcus lactis mutant. PLOS Genetics.

Rubin BE, Huynh TN, Welkie DG, Diamond S, Simkovsky R, Pierce EC, Taton A, Lowe LC, Lee JJ, Rifkin SA, Woodward JJ, Golden SS (2018). High-throughput interaction screens illuminate the role of c-di-AMP in cyanobacterial nighttime survival. Plos Genetics.

Townsley L, Yannarell SM, Huynh TN, Woodward JJ, Shank EA (2018). Cyclic di-AMP acts as an extracellular signal that impacts Bacillus subtilis biofilm formation and plant attachment. MBio.

Huynh TN, Choi PH, Sureka K, Ledvina HE, Campillo J, Tong L, Woodward JJ. (2016). Cyclic di-AMP targets the cystathionine beta-synthase domain of the osmolyte transporter OpuC. Molecular Microbiology.

Huynh, TN, and Woodward, JJ. (2015). Too much of a good thing: mechanisms for c-di-AMP depletion in the bacterial cytoplasm. Current Opinions in Microbiology.

 Huynh, TN., Luo, S., Pensinger, D., Sauer, J.D., Tong, L., and Woodward, J.J. (2015). An HD-domain phosphodiesterase mediates cooperative hydrolysis of c-di-AMP to affect bacterial growth and virulence. PNAS.

 Huynh, TN, Lin, HY, Noriega, CE, Lin, AV, Stewart, V. (2015). Crosstalk inhibition nullified by a receiver domain missense mutation. Journal of Bacteriology.

 Huynh, TN, Chen, LL, Stewart, V. (2015). Sensor-response regulator interactions in a cross-regulated signal transduction network. Microbiology.

Sureka, K, Choi, PH, Precit, M, Delince, M, Pensinger, DA, Huynh, TN, Jurado, AR, Goo, YA, Salidek, M, Iavarone, AT, Sauer, JD, Tong, L, Woodward, JJ. (2014). The cyclic dinucleotide c-di-AMP is an allosteric regulator of metabolic enzyme function. Cell

Huynh, TN, Noriega, CE, Stewart, V. (2013). Missense substitutions reflecting regulatory control of transmitter phosphatase activity in two-component signaling. Molecular Microbiology.

Seitzer, P., Huynh, TA,  Facciotti, M. T. (2013). JContextExplorer: a tree-based approach to facilitate cross-species genomic context comparison. BMC Bioinformatics.

 Huynh, TN, Stewart, V. (2011). Negative control in two-component signal transduction by transmitter phosphatase activity. Molecular Microbiology.

Huynh, TN, Noriega, CE, Stewart, V. (2010). Conserved mechanism for sensor phosphatase control of two-component signaling revealed in the nitrate sensor NarX. PNAS.